Raspberry Pi 4 Running Ubuntu 64 – mouse lag

Add usbhid.mousepoll=0 the end of line

sudo nano /boot/cmdline.txt
# OR
sudo nano /boot/firmware/cmdline.txt

For example

dwc_otg.lpm_enable=0 console=tty1 root=LABEL=writable rootfstype=ext4 elevator=deadline rootwait fixrtc quiet splash usbhid.mousepoll=0

Time-Line